DS-8X Eight Channel Spectrophotometer

Rapid Multichannel UV-Vis

Analyze 8 samples in as little as 10 seconds, or a single sample in 2 seconds.

GxP Compliance Ready

Optional 21 CFR Part 11 Software, IQ-OQ available. Flexible export in LIMS-compatible formats.

Eliminate Measurement Errors

Designed for sensitivity and accuracy, SmartPath™ technology algorithms provide real-time optimization of every sample.

Proven DeNovix Technology

Based on innovations that make DeNovix instruments trusted by scientists, the DS-8X ensures confidence in every measurement.

Maintenance-Free Design

Lifetime consistency; no recalibration required for the life of the instrument.

Powerful EasyApps™ Software

Easy-to-use, intuitive software designed by life scientists, for life scientists.

Optional 21 CFR Part 11 Software

EasyApps Secure provides an optional suite of software controls that allow regulated GxP facilities to easily add DS-8X instruments to their compliant workflows (view the compliance statement). The software is fully integrated within the onboard operating system and includes a range of features essential to ensuring compliance, including:

• Password protected system access
• Integrated electronic signature controls
• Comprehensive user account management
• Secure audit trail recording
• Advanced data handling and export tools

IQ-OQ Documentation

Full installation and qualification (IQ/OQ) package available.

LIMS Compatible

Flexible import and export options in LIMS-friendly formats.

Multi-Mode Flexibility

• Full spectrum UV-Vis: 190 – 840 nm

• Single Sample (2 sec); Up to Eight Samples (~10 sec)

• 1µL UV-Vis, Cuvette, and Fluorescence options

User-Friendly Pipette Guide

Our ergonomic pipette guide ensures error-free sample loading. Adjustable to accommodate for left- or right-handed users and any size pipette tip.

Stand-Alone (No PC)

Easy operation and no additional laptop or PC maintenance thanks to a 7 inch HD touchscreen, compatible with all common laboratory gloves.

LED Sample Tracker

Never lose track of where you are on your plate! This plug and play USB accessory links with the DS-8X to help guide your loading process. Software-controlled LEDs illuminate the correct sample column to measure based on your plate layout.

Set Up

Easily configure your plate setup to define sample IDs, blanks or empty wells.

• Option to import a pre-configured .csv file with your template
• Easily create, save, or edit plate templates or import from LIMS
• Experiment ID groups data for each plate for easy reference and data retrieval

Results

The DS-8X is equipped with pre-configured applications for each of the most commonly measured biomolecule types. All apps readily present results onscreen in as little as 10 seconds for eight sample mode, and 2 seconds for single sample mode.

• Concentration
• Purity Ratios / SmartQC Contamination Alerts
• Spectra Graphs

EasyApps™ Software

EasyApps software is designed by life scientists and combines with an intuitive touchscreen interface to ensure error-free operation. Every instrument is ready to go right out of the box – no PC set-up or software installation required.

Improve Workflow Efficiency

AutoRun makes quantification as easy as lifting, loading, and lowering. When AutoRun is turned on, simply lift the instrument arm and load your sample. The software will automatically initiate a measurement when the arm is closed. Sample tracking automatically progresses to the next sample column.

User Accounts & Data Handling

• Password-protected user accounts available
• All data is automatically saved and searchable in the Data App
• Easy to search, sort, and analyze archived data

Exporting & Connectivity

• Wi-Fi, Ethernet & USB connectivity
• Flexible export in LIMS-compatible formats
• Export via email, network & label printers, USB, and network drives
• Print microfuge tube labels using a DeNovix supported printer
• Print reports to a networked printer or DeNovix supported label printer

SmartQC™ Contamination Alerts

During measurements, SmartQC will check samples against well-established purity ratios. Samples that do not meet purity specifications will be flagged with visual alert icons. Tapping on an alert icon on the Run screen will provide detailed information regarding the possible reasons for the high or low value.

Nucleic Acid Quantification

• Measurement ranges
  • 2 – 11,000 ng/µL (dsDNA)
  • 1.6 – 8,800 ng/µL (RNA)
• Separate pre-configured apps for optimized workflow
• Sample contaminant alerts
• Pre-configured and user-defined factors for ssDNA ensures appropriate concentration calculations
• 260/280 and 260/230 ratios displayed
• 11 pre-configured dyes and fluorophores for Microarray
• Option to add an unlimited number of new dyes for quick recall in Microarray

       dsDNA                  RNA                 ssDNA             Microarray

Protein Quantification

• Measurement range
  • 0.1 – 330 mg/mL (BSA)
  • 0.6 – 161 mg/mL (IgG)
• Pre-configured and user-defined protein types for A280 and Labeled Proteins
• Pre-configured Peptide app for easy peptide analysis at A205/215
• Quick addition of new user defined protein types for improved workflow
• 11 pre-configured dyes and fluorophores for Labeled Proteins
• Option to add an unlimited number of new dyes for quick recall in Labeled Proteins
• BCA, Bradford, Lowry and 660 nm colorimetric assays optimized for ease of use
• Quick save and recall of standard curves available

          A280              Peptides       Labeled Proteins  Colorimetrics

Fluorescence Quantification

• Measurement ranges

  • *0.0005 ng/µL – 4000 ng/µL dsDNA

  • *0.25 – 1500 ng/µL RNA

• Four user-selectable LED light sources – compatible with all commonly used quantification assays e.g. DeNovix assays, Thermo Fisher Qubit™ assays, Thermo Fisher Quant-iT™ assays, and Promega Quantifluor™ assays

• Easy configuration of additional assays

• Single or multi-replicate standard curve options

• User control of line fit, trend line analysis, subtraction of blank

• User control of assay and reported sample concentration units

• Save and re-use curves and lists of standard concentrations

*Using DeNovix Fluorescence Quantification assays. For other kits please see manufacturer’s specifications.

Custom Fluorescence Apps

• Add new standard curve based fluorescent assays (nucleic assay, protein or other)
• Basic Fluorometer app returns RFU values for a wide range of fluorophores

Upgrade to fluorescence with the FX Module, and instantly access DeNovix fluorometer EasyApps

 Fluoro dsDNA      Fluoro RNA     Fluoro ssDNA    Fluoro Protein

Fluoro Custom Methods            Basic Fluorometer

UV-Vis and Custom Apps

• Simple but powerful apps enable measurement of more than just nucleic acids and proteins

• Full spectrum analysis (190 – 840 nm)

• Broad absorbance range for highly concentrated samples (up to 750 A, 1 cm equivalent)

• Add new user-defined standard curve methods

• Add custom formulas to eliminate downstream calculations

• Add kinetics methods (DS-8X+)

        UV-Vis                  Formula Methods    Standard Curve Methods

Kinetics and OD600

• DS-8X+ model enables cuvette-based kinetics studies

• Full spectrum analysis (190 – 840 nm), with dual or single wavelength monitoring

• Built-in heater with temperature control between 37° and 45° C.

• Dual graphs enable absorbance vs. time or absorbance vs. wavelength plots

• All kinetic data automatically saved to large on-board memory

• Estimated cell number calculator included in OD 600 app

       Kinetics             OD 600

Sample Tracker

The Sample Tracker USB accessory uses software-controlled LEDs to illuminate the correct sample column to measure on your plate.

FX Fluorometer Module

USB plug and play accessory to immediately enable DeNovix fluorometer EasyApps.

Cuvette Mode

Extend the lower detection limit with the built in cuvette option (DS-8X+)