Concentration: 1.0 mg/mL in 1 mM Sodium Citrate, pH 6.4
mRNA length: 1804 nucleotides.
MW MRNA46= 583820 g/mol; MRNA47= 590840 g/mol; MRNA48=587330 g/mol.
HA-H1N1 mRNA has been designed to produce high expression level of the (HA) hemagglutinin surface glycoproteins of H1N1 subtype of Influenza A virus.
OZB mRNAs are produced by in vitro transcription. mRNAs are stabilized at the 5’ end by modified nucleotides capping (Cap1) and contain a poly(A) tail at the 3’ end. Sequences have been optimized to yield improved stability and performance.
HA-H1N1 mRNAs:
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#MRNA46 does not bear any additional nucleotide modifications.
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#MRNA47 is modified with 5-methoxyuridine (5moU) to reduce innate immune response.
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#MRNA48 is modified with N1-methyl-pseudouridine (N1-mψ) to reduce innate immune response.
Size: 20 µg, 100µg or 1 mg.
Storage: -80°C
mRNAs ARE SHIPPED WITH DRY ICE