PhenoCode Signature Activated TIL Status Human Protein Panel

Overview 

The ability to determine whether tumor cells are proliferating and T cells are activated could provide important information about the anti-tumor response and be an indicator of prognosis. PhenoCode Signature Activated TIL Status panel (CD8, CD3, Ki-67, Granzyme B, PanCK) enables determination of Ki-67 positivity in addition to profiling of the tumor microenvironment for CD8+ T lymphocytes that are activated. Map additional phenotypes by adding a 6th marker to the panel from the antibody list below or add your own marker of interest by using the Antibody Conjugation Kit to barcode your antibody of choice.

Details

PhenoCode Signature panels are validated for the PhenoImager platform which integrates staining, imaging, and analysis using well-established workflows while providing accuracy and reproducibility. Featuring a flexible design component, PhenoCode Signature panels allow for the easy integration of a novel checkpoint or immune cell marker into a 5-plex base panel.

PhenoCode Signature Activated TIL Status Human Protein Panel contains:

• 5 Primary antibodies targeting CD3e, CD8, Granzyme, Ki67, and Pan-Cytokeratin
• 5 PhenoCode Signature Detectors
• 5 Opal dyes + DMSO for signal amplification: Opal 480, Opal Opal 570, Opal 620, Opal 690, Opal 780 + TSA-DIG
• 10X Spectral DAPI
• 1X Plus Automation Amplification Diluent
• PhenoCode Signature Diluent
• 1X Antibody Diluent/Block
• PhenoCode Signature Blocker 1
• PhenoCode Signature Blocker 5
• N Blocker
• J Blocker
• S Blocker

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PhenoImager™ HT