PhenoCode Signature Immune Profile Human Protein Panel

Overview

The composition of immune cells within the tumor microenvironment, such as T cells, B cells, and macrophages, varies between tumors and is strongly associated with outcomes to combination therapies. PhenoCode Signature Immune Profile panel enables profiling of the tumor microenvironment using 4 key immune cell markers (CD8, CD68, CD3, CD20) and a tumor marker (PanCK). Map additional phenotypes by adding a 6th marker to the panel from the antibody list below or add your own marker of interest by using the Antibody Conjugation Kit to barcode your antibody of choice.

Details

PhenoCode Signature panels are validated for the PhenoImager platform which integrates staining, imaging, and analysis using well-established workflows while providing accuracy and reproducibility. Featuring a flexible design component, PhenoCode Signature panels allow for the easy integration of a novel checkpoint or immune cell marker into a 5-plex base panel.

PhenoCode Signature Immune Profile Human Protein Panel contains:

• 5 Primary antibodies targeting CD3e, CD8, CD68, CD20, and Pan-Cytokeratin
• 5 PhenoCode Signature Detectors
• 5 Opal dyes + DMSO for signal amplification: Opal 480, Opal Opal 570, Opal 620, Opal 690, Opal 780 + TSA-DIG
• 10X Spectral DAPI
• 1X Plus Automation Amplification Diluent
• PhenoCode Signature Diluent
• 1X Antibody Diluent/Block
• PhenoCode Signature Blocker 1
• PhenoCode Signature Blocker 5
• N Blocker
• J Blocker
• S Blocker

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